"Defining Acute Traumatic Encephalopathy: Methods of the 'HEAD Injury Serum Markers and Multi-Modalities for Assessing Response to Trauma' (HeadSMART II) Study"

W Frank Peacock, Damon Kuehl, Jeff Bazarian, Adam J Singer, Chad Cannon, Zubaid Rafique, James P d’Etienne, Robert Welch, Carol Clark, Ramon Diaz-Arrastia

 Dec 2021 https://pubmed.ncbi.nlm.nih.gov/34956041/

Summary:

This protocol proposes to collect data using a multi-modality approach, including blood biomarkers, clinical characteristics, neurocognitive and neuropsychological assessments, to develop diagnostic and prognostic algorithms for ATE. The validation phase will determine the accuracy of the BRAINBox ATE Test as an aid to the diagnosis of ATE, and as an objective determination of a patient’s risk to develop post-concussive symptoms.